Duke vs. North Carolina prediction, picks for 2025 women's NCAA Tournament (2025)

Editor's note: Follow Duke vs. UNC women's basketball live updates and scores from their Sweet 16 game in March Madness.

The2025 women's NCAA Tournamentis in full force, folks.

Among the Friday Sweet 16 matchups will be a rivalry bout between Duke and North Carolina.

The No. 2 seed Duke Blue Devilsdefeated No. 15 Lehigh in the first round and No. 10 Oregon in the second round of thewomen's March Madness bracket. Duke's opponent, the 3-seeded North Carolina Tar Heels took down the No. 6 seed West Virginia Mountaineers in the Round of 32.

Here's how our experts see the Sweet 16 clash playing out. Be sure to check out USA TODAY's completeMarch Madness bracket breakdownfor in-depth analysis. While you're at it, don't forget to read our tournament upset picksandplayers who could make a splash.

Without further ado, here are our Duke vs. North Carolina picks and predictions.

Duke vs. North Carolina picks and predictions

Our experts from across the USA TODAY Network are favoring No. 2 Duke (4-1) on who will win the Sweet 16 game, the Blue Devils or Tar Heels. Take a look at their full bracket predictions.

Nancy Armour, USA TODAY: Duke

Jordan Mendoza, USA TODAY: North Carolina

Cydney Henderson, USA TODAY: Duke

Meg L. Hall, For The Win: Duke

Cora Hall, Knoxville News: Duke

Duke vs. North Carolina time, TV channel, how to watch

  • Game Day:Friday, March 28, 2025
  • Game Time:2:30 p.m. ET
  • Location:Legacy Arena in Birmingham, Alabama
  • TV Channel:ESPN
  • Live Stream:Fubo - Watch Now!

Watch Duke vs. North Carolina on Fubo

Duke vs. North Carolina odds

Odds via BetMGM as of Tuesday, March 25.

  • Spread: Duke -5.5
  • Moneyline Favorite:Duke -250
  • Moneyline Underdog:North Carolina +200
  • Total:124.5

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Duke vs. North Carolina prediction, picks for 2025 women's NCAA Tournament (2025)

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